Dr Sherif Wakil was the first practitioner in the UK to introduce the P-Shot® and O-Shot® for male and female sexual regeneration. In the first of a two-part article, he shares his experience with the P-Shot® and tells us how men can benefit from this new and exciting

Millions of men around the globe suffer from sexual health problems or insecurities about their manhood. For many men these problems increase with age and can dramatically impact their sexual performance and confidence. While these concerns are usually physical in nature they can also have a damaging psychological effect.

Although we can’t literally turn back the clock, advances in medical techniques mean that there is now a safe, effective and natural non-surgical option that doesn’t involve buying so-called “miracle pills” or gadgets over the internet. That solution is known as the P-Shot® Platelet Rich Plasma (PRP) procedure.

I am a strong believer in the power of PRP and the positive effect that it has on the various indications we use it for. As such, I always like to stay on top of new developments in this field. I heard about the P-Shot® (for male sexual enhancement) and O-Shot® (for female sexual enhancement) from my friend and colleague in the US, and the inventor of the treatments, Dr Charles Runels.

After reading all the reviews and data collected so far about these procedures, I made a decision to fly to the States to learn these latest ground breaking techniques and bring them back to the UK.


Named after the Greek god of fertility, the Priapus Shot®, or P-Shot®, is a pioneering new technique, which involves PRP being injected into the penis in order to rejuvenate it, improve sensation and function, increase size and girth, enhance sexual performance and improve erectile dysfunction.

The P-Shot® can also be used to treat Peyronie’s Disease, a condition in which patches of scar tissue develop along the shaft of the penis, resulting in bending of the penis, painful erections and difficulties with sexual intercourse.

The P-Shot® was invented back in 2010 by Dr Runels. He had been using hyaluronic acid fillers to treat patients’ lips and began to wonder if it was possible to get similar results using fillers on the penis. He decided against it, because of the rare side effects sometimes associated with hyaluronic acid fillers such as skin necrosis (skin tissue turns black and must be removed) and formation of lumps and nodules.

He then began studying PRP and its uses for skin rejuvenation, using natural growth factors in a patient’s own blood to stimulate the growth of healthy tissue. It’s the same technique that he used to develop the Vampire Facelift®.

When treating patients with the Vampire Facelift®, Dr Runels noticed that the side effects experienced with hyaluronic acid fillers never occurred. There has been no incidence of allergic reaction or necrosis of the skin, because the plasma is taken from the patient’s own body, and no incidence of lumpiness or nodules forming. In fact, all positive changes to patients’ face shape or blood flow came from the natural healing process of new tissue growth.

Based on this evidence, as well as the length of results (effects of PRP rejuvenation on the face last at least 18 months), Dr Runels decided to investigate the use of the technique on the penis, to treat erectile dysfunction. He found studies had been done investigating the effects of this treatment on animal penises, which found it caused new tissue growth and resulted in a bigger, harder penis. There were also studies demonstrating the effects of PRP therapy on erectile dysfunction. And the P-Shot® was born.


Just like the Vampire Facelift®, the P-Shot® uses the body’s natural healing and regenerating properties, injecting the growth-factor rich plasma from a patient’s own blood into the penis, which triggers stem cells to increase blood flow and generate healthy tissue growth.

A small amount of blood is taken from the patient’s arm and then placed in an FDA approved centrifuge where the plasma is harvested. The centrifuge I use is the same as that used by Dr Runels, which I brought in especially from the US. This is important as it guarantees better results and quality of the PRP harvested.

After the plasma has been harvested, it is placed in a separate vessel, where a few drops of activator e.g. calcium chloride solution are added to trick the platelets in the plasma into thinking the body has been injured so they release growth factors.

Now the plasma, which is rich in growth factors, is injected into the penis, into the two spongey cylinders of tissue that form the shaft (known as the corpus cavernosum), in a
specific way as per the protocol, which has been modified and mastered to give the best results.

The procedure itself takes around 40 minutes, and is performed under topical anaesthetic so there is little discomfort to the patient. One of the main advantages of the P-Shot® is that there is very little recovery time. Patients can return to normal day-to-day activities immediately, and even have sexual intercourse the same day as the treatment.
You only need one injection to see a difference, however, to enhance results patients

could receive two or three injections to see a more noticeable reduction in the symptoms.


Patients will notice an initial increase in volume, which comes from the growth factor-rich plasma injection. Over the following three days or so after the procedure, the fluid from the injection will be absorbed into the body.

New tissue growth will continue for at least 12 weeks after the procedure, giving the full, lasting results. Patients can then see an increase in volume again, often reaching a level similar to that experienced immediately following the procedure.

On average, patients see a 10-20% increase in the length and girth of the penis. Girth comes first, with the injection, followed by the length, which comes with continued growth.

Other results include:

  • Increase in sensation in the penis
  • Greater level of pleasure during sex
  • Increase in blood flow and circulation
  • Greater ability to achieve an erection
  • Increase in firmness of erections
  • Ability to maintain erections for longer, improving sexual performance

Because the procedure involves an injection of the patient’s own plasma and growth factors, there is no risk of an allergic reaction. Studies have also shown very little risk of lumps forming. Unlike many treatments for erectile dysfunction, the P-Shot® doesn’t have any associated cardiac risks, and it can be performed without damaging healthy tissue or nerve endings.

Millions of men around the world suffer in silence with problems to do with the look, feel, function and size of their genitals. The P-Shot® is a revolutionary solution to combat many common issues associated with sexual dysfunction.

Dr Sherif Wakil is the founder and medical director of DrSW Clinics and Royale Skin Clinics. As a national and international trainer for numerous aesthetic procedures including PRP Vampire treatments, the O-Shot® and P-Shot®, thread lifting and injectables, Dr Wakil has been invited to speak and share his skills at conferences and meetings around the world. He is a fellow of the International College of Surgeons and active member of several professional bodies including the General Medical Council, American Cosmetic Cellular Medicine Association, British College of Aesthetic Medicine. He is also the founder of the Royale Academy of Aesthetic Medicine where he teaches fellow medical practitioners his techniques.