The treatment involves the superficial injection of very small droplets of serums containing highly purified polynucleotides—DNA fragments extracted from salmon sperm cells or plants—directly into the skin to promote cellular regeneration, increase collagen production, and improve hydration.

Polynucleotides were first identified in the early 20th century when scientists discovered DNA as the carrier of genetic information. The therapeutic potential of polynucleotides began to be explored in the 1970s, largely thanks to pioneering researchers in regenerative medicine who recognized their ability to stimulate tissue repair and reduce inflammation. Initially used to aid wound healing and treat chronic ulcers, polynucleotide-based therapies have since evolved into popular skin rejuvenation treatments across Europe and Asia.

The key lies in both the biological activity of polynucleotides and their precise delivery. The injection technique places microdroplets just millimetres beneath the skin surface, allowing polynucleotides to stimulate fibroblast activity, reduce inflammation, and promote new blood vessel formation more effectively than topical or oral treatments.

This targeted approach supports the repair of damaged skin cells, improves skin elasticity, reduces fine lines and wrinkles, and enhances overall tone and texture.